XXII NATIONAL CONGRESS OF BIOCHEMISTRY
24-26 October 2024 | University of Aveiro
Program
VENUE
University of Aveiro - Rectorate Building
24 OCTOBER 2024
SESSION I
13:00 REGISTRATION
14:15 OPENING CEREMONY [NEUBERG AUDITORIUM]
Vítor Costa (SPB chair, UP), Margarida Fardilha (Congress chair, DCM-UA), Francisco Amado (Director of DCM-UA), Armando Silvestre (Director of DQ-UA), and Paulo Jorge Ferreira (Rector of UA)
14:30 Career Award Lecture - Miguel Seabra, NOVA Medical School, PT
Chairs: Graça Soveral (UL) and Duarte Barral (UNL)
15:30-16:30 SYMPOSIUM S1/S2 [Parallel Sessions]
Symposium S1 – Clinical Biochemistry and Therapeutics [WATSON HALL]
[Chairs: Vítor Costa (UP) and Cecília Santos (UBI)]
15:30-16:00 Giuseppe Calamita, University of Bari, IT
Aquaporins in acute inflammation and sepsis: the emerging role and therapeutic relevance of AQP9.
16:00-16:30 José Alexandre Ferreira, IPO-Porto, PT
Turning the glycocalyx into cancer vaccines: setting a new paradigm for cancer immunotherapy.
16:30-16:40 Sponsor SPECANALÍTICA | Ana Nogueira, SPECANALÍTICA, PT
CyBio FeliX: Automation as a partner in reducing hands on time in your multiplex cell assays.
Symposium S2 – Molecular Foundations of (Non-Communicable) Diseases: Understanding the Mechanisms Underlying Pathology I [NEUBERG AUDITORIUM]
[Chairs: Odete da Cruz e Silva (UA) and Tiago Gil Oliveira (UM)]
15:30-16:00 Mathieu Bollen, KU Leuven, BE
Protein phosphatase PP1 in health and disease.
16:00-16:30 Co-organized with SPN
Cláudia Almeida, NOVA Medical School, PT
Endosomal trafficking defects in brain aging and Alzheimer’s disease.
16:30 COFFEE BREAK and POSTER SESSION | Sponsored by DCM-UA
17:30 SELECTED ORAL COMMUNICATIONS S1/S2 [Parallel Sessions]
Symposium S1 [WATSON HALL]
[Chairs: Vítor Costa (UP) and Cecília Santos (UBI)]
17:30-17:42 Beatriz Paiva, FFUC, PT
Dietary nitrate reduces intestinal inflammation and sustains nitric oxide production in the human stomach under oral dysbiosis.
17:42-17:54 Heloísa de Souza Camilo, UAlgarve, PT
Biomedical applications of decavanadates with organic cations: Ca2+-ATPase and P-gp inhibition potentials and antibacterial activities.
17:54-18:06 Inês Castro-Almeida, i3S, PT
AHR on T(AHR)get: dissecting the impact of Aryl Hydrocarbon Receptor modulation in disease and therapy.
18:06-18:18 Rúben Moreira, UA, PT
Impact of chromium picolinate steroidogenesis and antioxidant balance in Leydig cell using an in vitro insulin resistance model.
18:18-18:30 Tomás Vieira, IMM, PT
Harnessing the biomedical potential of 1-hydroxyphenazine against Staphylococcus aureus biofilms.
Symposium S2 [NEUBERG AUDITORIUM]
[Chairs: Odete da Cruz e Silva (UA) and Tiago Gil Oliveira (UM)]
17:30-17:42 Catarina Marreiros, UAlgarve, PT
Gla rich protein as a promising biochemical marker for cardiovascular risk evaluation in chronic kidney disease.
17:42-17:54 Maria Carmona Gouveia, Imperial College London, UK
Investigating the role of CTCF in stress-induced senescence in astrocytes.
17:54-18:06 Filipa Silva, UC, PT
The impact of nutrient sensing on lysosome-mitochondria contact sites.
18:06-18:18 Paulo Gameiro, NOVA Medical School, PT
A bioenergetic-signalling paradigm to decode TCA cycle (dys)function in health and disease states.
18:18-18:30 Paulo Gaspar, INSA, PT
Abnormalities in LIMP-2 knockout mice: investigating the role of LIMP-2 in lipid metabolism.
18:30-19:30 WELCOME RECEPTION | Sponsored by Bruker
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25 OCTOBER 2024
SESSION II
8:30-10:30 SYMPOSIUM S3 - Biosciences Education [NEUBERG AUDITORIUM]
[Chair: Rui Oliveira (UMinho) and Manuel João Costa (UMinho)]
8:30 Introduction - Biosciences education: the current landscape and our next steps - Rui Oliveira and Manuel João Costa, UMinho, PT
8:45 PLENARY LECTURE I | FEBS EDUCATION NATIONAL LECTURE
Thomas Lancaster, Imperial College London, UK
Academic integrity in the generative AI age.
9:15 Workshop | Engaging conversations among participants to delve into the future of bioscience education - Margarida Fardilha, UA, PT, and Rui Oliveira, UMinho, PT
10:15 Debriefing - Take home messages
10:30 COFFEE BREAK and POSTER SESSION
11:00 PLENARY LECTURE II - Iseult Lynch, University of Birmingham, UK
Translating mechanistic understanding of nanomaterials impacts of living organisms into adverse outcome pathways.
[Chairs: Manuel Aureliano (UAlgarve) and Célia Antunes (UÉvora)]
12:00-13:00 SYMPOSIUM S3/S4/S5 [Parallel Sessions]
Symposium S3 – Workshop | Lab simulations, smart worksheets: transforming science education, empowering educators to inspire the next generation of scientists.*
[KREBS HALL] [Chair: Maria João Neuparth (CESPU-UP)]
12:00-13:00 Bill Heslop, LearnSci, UK
*Contact the organizing committee to schedule a private meeting with LearnSci during the congress (1h available/day).
Symposium S4 – Exploring Environmental Driven Effects: Unveiling the Interconnections
[NEUBERG AUDITORIUM] [Chairs: Francisco Peixoto (UTAD) e Rosário Domingues (UA)]
12:00-12:30 Luís Taborda Barata, UBI, PT
You are what you breathe: deleterious exposome-induced respiratory effects.
SELECTED ORAL COMMUNICATIONS S4
12:30-12:40 Mónica Garcia, UTAD, PT
Assessing mitochondrial and antioxidant function in FVB/n mouse kidney: comparative toxicity of fluorescent and non-fluorescent micro-nanoplastics.
12:40-12:50 João A. Rodrigues, CICECO-UA, PT
Exposure of non-target aquatic organisms to endocrine disruptors in a temperature rise scenario disrupts basal metabolism - a NMR metabolomics study.
12:50-13:00 Célia Antunes, UÉvora, PT
Unraveling 20-year allergy risk in Alentejo, Portugal.
Symposium S5 – Molecular Foundations of (Communicable) Diseases: Understanding the Mechanisms Underlying Pathology II
[WATSON HALL] [Chairs: Paula Ludovico (UMinho) and João Laranjinha (UC)]
12:00-12:30 Miguel Castanho, UL, PT
From molecules to mice, from Zika virus to Disease X - developing a broad spectrum antiviral able to reach the brain and placenta.
SELECTED ORAL COMMUNICATIONS S5
12:30-12:40 Pedro O. Corda, iBiMED-UA, PT
SARS-CoV-2 nucleoprotein recruits Protein Phosphatase 1 (PP1) to dephosphorylate Glycogen Synthetase Kinase 3 (GSK3).
12:40-12:50 Carolina Ruivinho, BioISI-FCUL, PT
Identification of novel viral miRNA-like molecules with a potential role in HIV pathogenesis.
12:50-13:00 Gonçalo C. Justino, CQE-IMS, PT
Enhancing the preparedness toolbox through a post-omics expedition - unveiling the COVID molecular signature on biochemical pathways.
13:00 GROUP PHOTO AND LUNCH
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SESSION III
14:30 PLENARY LECTURE III [NEUBERG AUDITORIUM] - Co-organized with SEBBM
Fernando Corrales, Spanish National Centre for Biotechnology, ES
Proteomics: a toolbox for understanding liver biology and disease.
[Chairs: Pedro Domingues (UA) and Francisco Ambrósio (UC)]
15:30-17:00 SYMPOSIUM S6/S7 [Parallel Sessions]
Symposium S6 – Harmony in Diversity: Global Perspectives on Omics in Biochemistry
[NEUBERG AUDITORIUM] [Chairs: Manuel Santos (UC) and Carlos Farinha (UL)]
15:30-16:00 Johannes Swinnen, KU Leuven, BE
Spatial multi-omics as a tool to map tissue heterogeneity and to identify exploitable lipid metabolic vulnerabilities in cancer.
16:00-16:30 Sílvia Rocha, UA, PT
Metabolomics - a key player in the construction of the future One-Health research.
SELECTED ORAL COMMUNICATIONS S6
16:30-16:40 Patrícia Sousa, UMadeira, PT
MALDI-TOF MS-based urinary peptidomics biosignature of breast cancer as a powerful approach for diagnosis.
16:40-16:50 Pedro C. Rosado, CQE-IMS, PT
Mapping New Druggable Sites in methicillin-resistant Staphylococcus aureus: a post-omics approach to the ESKAPE pathogens.
16:50-17:00 Paulo Gaspar, INSA, PT
Metabolomics and a non-invasive method to identify of lysosomal storage disorders.
Symposium S7 – SPBf session: Proteins in action
[WATSON HALL] [Chairs: Armindo Salvador (CNC-UC) and Sandra M. Ribeiro (i3S)]
15:30-15:50 Co-organized with SBBq
Chuck S. Farah, University of São Paulo, BR
Structural and functional studies on a bactericidal type IV secretion system.
15:50-16:10 Ana Melo, UL, PT
Untangling the initial membrane-binding of tau protein at the single-molecule level.
16:10-16:30 Pedro Fernandes, UP, PT
Snake venom: toxin-based drugs and drugs for toxins.
SELECTED ORAL COMMUNICATIONS S7
16:30-16:40 Duangnapa Kiriwan, LAQV/REQUIMTE - BioSIM, PT
Tripeptide-based inhibition of EGFR tyrosine kinase in lung cancer: findings from computational and experimental studies.
16:40-16:50 Fábio Martins, LAQV/REQUIMTE - BioSIM, PT
Development of a computational protocol for the rational design of nanomedicines aimed at cardiovascular diseases.
16:50-17:00 Tânia Francisco, IBMC/i3S, PT
Nonconventional ubiquitination at a cysteine residue: protecting PEX5 from overubiquitination.
17:00 COFFEE BREAK and POSTER SESSION | Sponsored by LICORbio
18:00-19:30 SYMPOSIUM S8 | Biochemistry in Motion: Driving Practical Applications for Society and Sustainable Development Goals through Innovative Product Design | Organized by the SPB Junior Section
[NEUBERG AUDITORIUM] [Chairs: Vitória Baptista (UMinho) and Ana Galveias (UÉvora)]
18:00-18:30 Fadhil Musa, Delox, PT
From Technology to Market: How DeloxHP is Transforming Bio-decontamination.
SELECTED ORAL COMMUNICATIONS S8
18:30-18:45 Diana Costa, UC, PT
Acetylcholinesterase response to root-knot nematode management sustainable technology.
18:45-19:00 Amid Mostafaie, UA, PT
Improving soil quality with olive pomace-based entomofertilizer from Hermetia illucens.
19:00-19:15 Beatriz Velosa da Fonseca, ICVS-UMinho, PT
Enhancing human Malaria parasites for large-scale multistage drug screening.
SELECTED FLASH TALKS S8
19:15-19:20 Paula A. Lopes, FMV-UL, PT
Behavioural hallmarks in Alzheimer’s disease 5xFAD mice fed sustainable DHA-enriched diets.
19:20-19:25 Tiago Coutinho, CITAB-UTAD, PT
Assessment of the antioxidant, safety profile and anti-inflammatory activity of two flavonoids: taxifolin and silybin.
19:25-19:30 Questions
20:00 CONGRESS DINNER
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26 OCTOBER 2024
SESSION IV
9:00 PLENARY LECTURE IV [NEUBERG AUDITORIUM] - Caroline Dean, John Innes Centre, UK
Polycomb memory to register environmental exposure.
[Chairs: Margarida Oliveira (ITQB-UNL) and José de S. Câmara (UMadeira)]
10:00 COFFEE BREAK and POSTER SESSION | Sponsored by DCM-UA
10:30-12:00 SYMPOSIUM S9/S10 [Parallel Sessions]
Symposium S9 – SPBP session: Plant Biochemistry [NEUBERG AUDITORIUM]
[Chairs: Margarida Oliveira (ITQB-UNL) and Maria Manuela Costa (UM)]
10:30-11:00 Elena Baena-Gonzalez, University of Oxford, UK Regulation of plant growth by the energy signaling pathway.
11:00-11:30 Pedro Humberto Castro, BIOPOLIS-CIBIO, PT SUMOylation, the hallmark of the environmental stress response in plants.
SELECTED ORAL COMMUNICATIONS S9
11:30-11:40 Diana Matos, CESAM-UA, PT
Biocontrolling late wilt in maize: effects of bacterial inoculation on the biochemistry, physiology and nutritional status of infected plants.
11:40-11:50 Sara Coelho, CBMA-UMinho, PT
Unveil the function of the DDR gene regulatory model in the bryophyte Marchantia polymorpha.
11:50-12:00 Cecília Calado, COPELABS-ULusófona, PT
Development of a biomarker related to the antimicrobial effect of the macroalgae extracts based on the FTIR spectra and chemometrics techniques.
Symposium S10 – Food Biochemistry [WATSON HALL]
[Chairs: Sílvia Rocha (UA) and José de S. Câmara (UMadeira)]
10:30-11:00 Christophe Courtin, KU Leuven, BE
Leveraging biochemistry for healthy foods.
11:00-11:30 Maria do Céu Costa, Lusófona University, PT
Myths and facts about food supplements: are there hidden benefits and dangers?
SELECTED ORAL COMMUNICATIONS S10
11:30-11:40 Carlos M. Gomes, CITAB-UTAD, PT
Salvianolic acid A induces prophylactic antioxidant protection against oxidative damage in Caco-2 cells through Nrf2 activation.
11:40-11:50 Bernardo Ferreira, UA, PT
Phosphate’s role in meat products and potential alternatives.
11:50-12:00 Raquel N. da Silva, FCUP, PT
Turning juice by-products into nutrient-rich snacks: a circular economy strategy.
12:00 CLOSING CEREMONY AND PRIZES [NEUBERG AUDITORIUM]
12:30 LUNCH